Is Oxytocin Induction at Labor a Risk Factor for Developmental Hip Dysplasia?
<b>Background:</b> Developmental hip dysplasia is a common condition with preventable causes, and its etiology is still not fully elucidated. In our study, we aimed to examine the use of synthetic oxytocin during childbirth as a potential risk factor for developmental hip dysplasia. <b>Methods:</b> This study involved comprehensive hip examinations on postnatal days 0, 14, 30, and 60, as well as hip ultrasonography results at 6-8 weeks. We specifically focused on healthy girls born with vaginal deliveries, comparing those who were applied with a low-dose oxytocin induction protocol (Group 2) and those who had vaginal deliveries without induction (Group 1). <b>Results:</b> When the examination findings were compared with the hip ultrasonography findings (Type 2a was detected in the left hip of one patient (6.3%) in Group 1 and in the right hip of two patients (11.8%) in Group 2), it was seen that oxytocin induction did not cause a risk for developmental hip dysplasia. The oxytocin induction rate was higher in newborns weighing more than 3400 g (<i>p</i> = 0.04). <b>Conclusions:</b> A low-dose oxytocin protocol applied at birth has not been shown to harm the hip joint in the neonatal period and on ultrasonographic α and β angle measurements applied at 6-8 weeks. However, our study also highlights the need for new studies investigating oxytocin peripheral receptors and their effects, underscoring the importance of our findings in guiding future research in this area.
Authors
- Lütfiye İdil Emral
- Ersin Taşkın (ORCID: https://orcid.org/0000-0002-5086-008X)
- Demet Soylu
- Aysun Albayrak
- Memnune Arslan
Institutions
- Sivas State Hospital (TR)
- Lokman Hekim Üniversitesi (TR)
Publication Details
- Journal
- Journal of Clinical Medicine
- Published
- 2024-09-26
- DOI
- https://doi.org/10.3390/jcm13195724
- Primary Topic
- Neuroendocrine regulation and behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.00