Efficacy and safety of different oral prednisone tapering courses in adult anti‐<scp>NMDAR</scp> encephalitis: A multicenter prospective cohort study
Longer oral prednisone courses for adult patients with anti-NMDAR encephalitis did not show superior effects compared to shorter courses in improving modified Rankin Scale (mRS) scores and CASE scores, reducing the risk of relapse within 2 years, or achieving seizure freedom. Instead, extended prednisone courses may lead to more side effects- particularly weight gain. This outcome recommends evaluating the possibility of shortening the duration of oral prednisone after a thorough patient assessment.
Authors
- Ammar Taha Abdullah Abdulaziz (ORCID: https://orcid.org/0000-0003-3333-4800)
- Aiqing Li (ORCID: https://orcid.org/0000-0002-8630-6611)
- Xueying Kong
- Dong Chi Zhou (ORCID: https://orcid.org/0000-0001-7101-4125)
- Kundian Guo (ORCID: https://orcid.org/0000-0003-4512-4296)
- Zhen Hong (ORCID: https://orcid.org/0000-0002-0014-6873)
- Xue Gong (ORCID: https://orcid.org/0000-0001-9383-8539)
- Linjun Cai (ORCID: https://orcid.org/0000-0002-3683-4934)
- Jinmei Li (ORCID: https://orcid.org/0000-0002-7411-8269)
- Gaowei Li
- Xu Liu
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Shanghai Center for Brain Science and Brain-Inspired Technology (CN)
- Second Affiliated Hospital of Chengdu University of Traditional Chinese (CN)
Publication Details
- Journal
- Epilepsia
- Published
- 2024-09-26
- DOI
- https://doi.org/10.1111/epi.18107
- Citations
- 4
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.48
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Sichuan University
- Natural Science Foundation of Sichuan Province
- National Key Research and Development Program of China
- West China Hospital, Sichuan University