Efficacy and safety of selexipag in patients with inoperable or persistent/recurrent CTEPH (SELECT randomised trial)

SELECT was discontinued for futility, as no treatment effect on the primary end-point (PVR) was observed. Safety data were consistent with the established safety profile of selexipag, with no new safety signals identified.

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Publication Details

Journal
European Respiratory Journal
Published
2024-09-26
DOI
https://doi.org/10.1183/13993003.00193-2024
Citations
9
Primary Topic
Pulmonary Hypertension Research and Treatments
Type
article
Field-Weighted Citation Impact
3.77

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article

Efficacy and safety of selexipag in patients with inoperable or persistent/recurrent CTEPH (SELECT randomised trial)

Joanna Pepke‐Żaba, Nick H. Kim, Julian Ilcheff Borissoff, S. Gesang et al.
9 citations
European Respiratory Journal
Pulmonary Hypertension Research and Treatments
3.77
article

Efficacy and safety of selexipag in patients with inoperable or persistent/recurrent CTEPH (SELECT randomised trial)

Joanna Pepke‐Żaba, Nick H. Kim, Julian Ilcheff Borissoff, S. Gesang, Michael M. Madani, Marion Delcroix, Richard N. Channick, Hossein Ardeschir Ghofrani, Valerie Easton, Dominik Richard
article en
9 citations

Abstract

SELECT was discontinued for futility, as no treatment effect on the primary end-point (PVR) was observed. Safety data were consistent with the established safety profile of selexipag, with no new safety signals identified.

European Respiratory JournalVol. 64(4)
Royal Papworth Hospital (GB), UCLA Health (US), UC San Diego Health System (US), UCLA Medical Center (US), University of California San Diego (US), Universities of Giessen and Marburg Lung Center (DE), Actelion (Switzerland) (CH), KU Leuven (BE)
Actelion Pharmaceuticals
Good health and well-being
Openalex Percentile: Top 6%
Pulmonary Hypertension Research and Treatments
3.77
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