Single-cell sequencing reveals cellular landscape alterations in the airway mucosa of patients with pulmonary long COVID

A single-cell transcriptomic landscape of the small airways suggest that neutrophils may play a significant role in mediating the chronic small airway inflammation driving pulmonary symptoms of long COVID.

Authors

Institutions

Publication Details

Journal
European Respiratory Journal
Published
2024-09-26
DOI
https://doi.org/10.1183/13993003.01947-2023
Citations
17
Primary Topic
Respiratory Support and Mechanisms
Type
article
Field-Weighted Citation Impact
7.12

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Single-cell sequencing reveals cellular landscape alterations in the airway mucosa of patients with pulmonary long COVID

Jonathon A Leipsic, Stephen B Milne, Elizabeth Guinto, Graeme J. Koelwyn et al.
17 citations
European Respiratory Journal
Respiratory Support and Mechanisms
7.12
article

Single-cell sequencing reveals cellular landscape alterations in the airway mucosa of patients with pulmonary long COVID

Jonathon A Leipsic, Stephen B Milne, Elizabeth Guinto, Graeme J. Koelwyn, Rachel L. Eddy, Don D. Sin, Hong Dang, Tawimas Shaipanich, Chen Xi Yang, Clarus Leung, Tara Stach, Dina Yehia, Hye Yun Park, Firoozeh V. Gerayeli, Chung Yan Cheung, Seyed Milad Vahedi, Josie Tuong, Xuan Li, Janice M. Leung, Cassie Gilchrist, Julia Sw Yang
article en
17 citations

Abstract

A single-cell transcriptomic landscape of the small airways suggest that neutrophils may play a significant role in mediating the chronic small airway inflammation driving pulmonary symptoms of long COVID.

European Respiratory JournalVol. 64(5)
University of North Carolina at Chapel Hill (US), University of British Columbia Hospital (CA), The University of Sydney (AU), New York City Fire Department (US), University of British Columbia (CA), Simon Fraser University (CA), St. Paul's Hospital (CA), Samsung Medical Center (KR), Health First (US), Sungkyunkwan University (KR)
Genome British Columbia, Mitacs, University of British Columbia, Canadian Institutes of Health Research
Openalex Percentile: Top 2%
Respiratory Support and Mechanisms
7.12
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.