Oral Microbiome and Subsequent Risk of Head and Neck Squamous Cell Cancer
This case-control study yielded compelling evidence that oral bacteria are a risk factor for HNSCC development. The identified bacteria and bacterial complexes hold promise, along with other risk factors, to identify high-risk individuals for personalized prevention of HNSCC.
Authors
- Qiuyin Cai (ORCID: https://orcid.org/0000-0002-9384-5648)
- Marjorie L. McCullough (ORCID: https://orcid.org/0000-0003-3025-6341)
- Feng Wu (ORCID: https://orcid.org/0000-0003-3670-7895)
- Richard B. Hayes (ORCID: https://orcid.org/0000-0002-0918-661X)
- Mykhaylo Usyk (ORCID: https://orcid.org/0000-0002-0374-3753)
- Martha J. Shrubsole (ORCID: https://orcid.org/0000-0002-5591-7575)
- Soyoung Kwak (ORCID: https://orcid.org/0000-0003-4046-5251)
- Jiyoung Ahn (ORCID: https://orcid.org/0000-0002-2900-2304)
- Neal D. Freedman (ORCID: https://orcid.org/0000-0003-0074-1098)
- Caroline Y. Um (ORCID: https://orcid.org/0000-0001-5449-6230)
- Chan Wang (ORCID: https://orcid.org/0000-0002-1718-5414)
- Huilin Li (ORCID: https://orcid.org/0000-0002-8288-7068)
- Wen‐Yi Huang (ORCID: https://orcid.org/0000-0002-4440-3368)
Institutions
- American Cancer Society (US)
- Vanderbilt University (US)
- National Cancer Institute (US)
- Vanderbilt-Ingram Cancer Center
- NYU Langone’s Laura and Isaac Perlmutter Cancer Center
- Division of Cancer Epidemiology and Genetics
- New York University (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- JAMA Oncology
- Published
- 2024-09-26
- DOI
- https://doi.org/10.1001/jamaoncol.2024.4006
- Citations
- 32
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 12.81