Poor Response to Bevacizumab Correlates With Higher IL-6 and IL-8 Aqueous Cytokines in AMD
Aqueous IL-6 and IL-8 may be important markers of treatment response or poor response in nAMD. Future therapeutic strategies may include targeted treatment against both vascular endothelial cell growth factor (VEGF) and IL-6 and/or IL-8 in patients who do not respond to anti-VEGF treatment alone.
Authors
- Emma Connolly (ORCID: https://orcid.org/0000-0002-6964-6139)
- Sarah Doyle (ORCID: https://orcid.org/0000-0002-6294-9380)
- Kiva Brennan (ORCID: https://orcid.org/0000-0003-4960-7076)
- Mark Cahill
- Ghaleb El-Farouki
Institutions
- Trinity College Dublin (IE)
- Royal Victoria Eye and Ear Hospital (IE)
- Progress (Ireland) (IE)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2024-09-26
- DOI
- https://doi.org/10.1167/iovs.65.11.37
- Citations
- 4
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.15
Funders
- Medical Research Charities Group
- Science Foundation Ireland
- Irish Research Council
- Royal Victorian Eye and Ear Hospital