Limited cerebellar gradient extension in temporal lobe epilepsy with dystonic posturing
Dystonic posturing contralateral to epileptic focus is a common symptom in temporal lobe epilepsy, and the cerebellum may be involved in its generation. In this study, we found cerebellar gradients alterations in functional connectivity in temporal lobe epilepsy patients with and without contralateral dystonic posturing. In particular, we found that TLE patients with dystonic posturing may have more limited cerebellar gradient in functional connectivity, involving more contribution of cerebellar motor function to ipsilateral cerebellar gradient. Our study suggests a close relationship between ipsilateral cerebellum and contralateral dystonic posturing.
Authors
- Cheng Luo (ORCID: https://orcid.org/0000-0003-0524-5886)
- Dongmei An (ORCID: https://orcid.org/0000-0003-4622-0837)
- Sisi Jiang (ORCID: https://orcid.org/0000-0002-7430-9639)
- Junxia Chen (ORCID: https://orcid.org/0000-0002-8531-7562)
- Dong Chi Zhou (ORCID: https://orcid.org/0000-0001-7101-4125)
- Qiyong Gong (ORCID: https://orcid.org/0000-0002-5912-4871)
- Yingjie Qin (ORCID: https://orcid.org/0000-0002-6020-5900)
- Wei Li (ORCID: https://orcid.org/0000-0001-7654-3069)
- Heng Zhang (ORCID: https://orcid.org/0000-0001-8866-0932)
- Xiuli Li
Institutions
- University of Electronic Science and Technology of China (CN)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Epilepsia Open
- Published
- 2024-09-26
- DOI
- https://doi.org/10.1002/epi4.13056
- Citations
- 1
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- National Natural Science Foundation of China
- Sichuan University
- Natural Science Foundation of Sichuan Province
- West China Hospital, Sichuan University