Pharmacokinetics-Based Safety Evaluation in Half-Dose Verteporfin Photodynamic Therapy

The results of this study indicate that precautionary measures should be taken to avoid sunlight following both half and conventional doses of PDT during the similar post-treatment periods of two days. Nevertheless, given the substantially higher plasma concentration levels associated with conventional-dose PDT compared with the half-dose, systemic safety should be carefully considered when administering conventional-dose PDT.

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Publication Details

Journal
Ophthalmic Research
Published
2024-09-26
DOI
https://doi.org/10.1159/000541619
Primary Topic
Photodynamic Therapy Research Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Pharmacokinetics-Based Safety Evaluation in Half-Dose Verteporfin Photodynamic Therapy

Jae‐Yong Chung, Se Joon Woo, Hyeong Min Kim, Hyuncheol Kim
Ophthalmic Research
Photodynamic Therapy Research Studies
article

Pharmacokinetics-Based Safety Evaluation in Half-Dose Verteporfin Photodynamic Therapy

Jae‐Yong Chung, Se Joon Woo, Hyeong Min Kim, Hyuncheol Kim
article en

Abstract

The results of this study indicate that precautionary measures should be taken to avoid sunlight following both half and conventional doses of PDT during the similar post-treatment periods of two days. Nevertheless, given the substantially higher plasma concentration levels associated with conventional-dose PDT compared with the half-dose, systemic safety should be carefully considered when administering conventional-dose PDT.

Ophthalmic ResearchVol. 67(1)
Sogang University (KR), Konkuk University (KR), Seoul National University Bundang Hospital (KR)
Seoul National University Bundang Hospital, Seoul National University
Good health and well-being
Openalex Percentile: Top 70%
Photodynamic Therapy Research Studies
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