Severe Optic Neuropathy Induced by Very Prolonged Tedizolid as Suppressive Therapy: Description of a Case Report and Implication for Better Assessment
The long-term tolerability of linezolid is low because of mitochondrial toxicity, whereas tedizolid may represent a better option for suppressive therapy. We report a first presumed case of tedizolid-associated optic neuropathy after a very prolonged (18-month) intake and believe that screening for optic neuropathy should be considered for patients undergoing tedizolid suppression.
Authors
- Mehdi Ouaïssi (ORCID: https://orcid.org/0000-0002-0906-4428)
- Marie‐Laure Le Lez
- Raoul Kanav Khanna (ORCID: https://orcid.org/0000-0001-6032-1488)
- Nathalie Pansu (ORCID: https://orcid.org/0000-0002-3702-4589)
- Eve-Marie Thillard (ORCID: https://orcid.org/0000-0002-4597-1738)
- François Coustillères (ORCID: https://orcid.org/0000-0002-4034-9341)
- S Olivereau
Institutions
- Université de Tours (FR)
- Inserm (FR)
- Université de Montpellier (FR)
- Centre Hospitalier Universitaire de Montpellier (FR)
- Services déconcentrés d'appui à la recherche Val de Loire (FR)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1093/ofid/ofae517
- Citations
- 5
- Primary Topic
- Retinal and Optic Conditions
- Type
- article
- Field-Weighted Citation Impact
- 2.69