Thermodynamic and kinetic effects on the activity and selectivity of antimicrobial peptides

What have we learned about antimicrobial peptides (AMPs)? Produced by all organism Short sequences (10-50 a.a.) Cationic and amphipatic Kill pathogens rapidly by making their membrane permeable Selective (due to the different composition of bacterial and host membranes)

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Publication Details

Published
2024-09-20
DOI
https://doi.org/10.17952/37eps.2024.p2088
Primary Topic
thermodynamics and calorimetric analyses
Type
article
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Thermodynamic and kinetic effects on the activity and selectivity of antimicrobial peptides

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2 links
thermodynamics and calorimetric analyses
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Thermodynamic and kinetic effects on the activity and selectivity of antimicrobial peptides

Stefano Gianni, Maria Rosa Loffredo, Daniela Roversi, Angelo Toto, Henrik Franzyk, Maria Luisa Mangoni, Cassandra Troiano, Giuseppe Giaquinto, Federico Carneri, E. Franci, A. Leoci, Lucien Stella, Y. Park
article en

Abstract

What have we learned about antimicrobial peptides (AMPs)? Produced by all organism Short sequences (10-50 a.a.) Cationic and amphipatic Kill pathogens rapidly by making their membrane permeable Selective (due to the different composition of bacterial and host membranes)

Medical University of Sofia (BG)
Openalex Percentile: Top 81%
thermodynamics and calorimetric analyses
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