Baseline MRI predictors of successful organ preservation in the Organ Preservation in Rectal Adenocarcinoma (OPRA) trial
Baseline MRI features, including nodal disease, extramural venous invasion, mesorectal fascia involvement, and tumour length, independently predict the likelihood of organ preservation after completion of total neoadjuvant therapy. Mesorectal fascia involvement and nodal disease are associated with disease-free survival.
Authors
- Jin K. Kim (ORCID: https://orcid.org/0000-0002-4373-1431)
- Garrett M. Nash (ORCID: https://orcid.org/0000-0001-9833-2625)
- Madhulika G. Varma (ORCID: https://orcid.org/0000-0003-1679-926X)
- Li‐Xuan Qin (ORCID: https://orcid.org/0000-0002-9367-3807)
- Andrew J. Gregory (ORCID: https://orcid.org/0000-0003-1905-3236)
- Julio García‐Aguilar (ORCID: https://orcid.org/0000-0003-2451-0948)
- Floris S. Verheij (ORCID: https://orcid.org/0000-0001-7834-7336)
- Martin R. Weiser (ORCID: https://orcid.org/0000-0002-9577-7984)
- Matthew J. Lee (ORCID: https://orcid.org/0000-0001-9971-1635)
- Richard F. Dunne (ORCID: https://orcid.org/0000-0001-6608-660X)
- Ana Gleisner (ORCID: https://orcid.org/0000-0002-5040-4105)
- Abraham J. Wu (ORCID: https://orcid.org/0000-0002-2597-7091)
- José G. Guillem (ORCID: https://orcid.org/0009-0002-5455-4749)
- Joseph C. Carmichael (ORCID: https://orcid.org/0000-0003-2738-7113)
- Maria Widmar (ORCID: https://orcid.org/0000-0002-1145-8370)
- H M Thompson
- Leonard B. Saltz (ORCID: https://orcid.org/0000-0001-8353-4670)
- Rona Yaeger (ORCID: https://orcid.org/0000-0002-7233-5454)
- S Oommen (ORCID: https://orcid.org/0000-0003-4383-1587)
- Dana M. Omer (ORCID: https://orcid.org/0000-0002-2259-2540)
- Karyn A. Goodman (ORCID: https://orcid.org/0000-0002-4576-6355)
- Daniel O. Herzig (ORCID: https://orcid.org/0000-0001-8039-2136)
- J. Joshua Smith (ORCID: https://orcid.org/0000-0003-2538-5456)
- Andrew L. Coveler (ORCID: https://orcid.org/0000-0003-1710-5637)
- Neil H. Segal (ORCID: https://orcid.org/0000-0002-3047-2303)
- Blasé N. Polite (ORCID: https://orcid.org/0000-0001-8743-8096)
- Marc J. Gollub (ORCID: https://orcid.org/0000-0002-6008-0730)
- Sujata Patil (ORCID: https://orcid.org/0000-0003-1706-5321)
- Iris H. Wei (ORCID: https://orcid.org/0000-0001-9006-9105)
- Emmanouil P. Pappou (ORCID: https://orcid.org/0000-0002-8735-1852)
- Jorge Marcet (ORCID: https://orcid.org/0000-0003-3728-8741)
- Steve Hunt
- Sabrina T. Lin (ORCID: https://orcid.org/0000-0001-7535-2535)
- Charles A. Ternent (ORCID: https://orcid.org/0000-0003-0050-9723)
- Jonathan Benjamin Yuval (ORCID: https://orcid.org/0000-0002-9251-8303)
- David Liska (ORCID: https://orcid.org/0000-0002-8632-6065)
- Philip B. Paty (ORCID: https://orcid.org/0000-0002-7045-2112)
- Charles M. Friel
- Michael R. Marco (ORCID: https://orcid.org/0000-0001-6731-0810)
- Brian L. Bello (ORCID: https://orcid.org/0009-0000-2307-8861)
- A. Cercek
- Tae-Hyung Kim (ORCID: https://orcid.org/0000-0002-5045-4401)
- John C. Krauss (ORCID: https://orcid.org/0000-0002-5197-736X)
- Hannah Williams (ORCID: https://orcid.org/0000-0001-8928-4190)
- P Cataldo
- Larissa K. Temple
- João Miranda
Institutions
- Memorial Sloan Kettering Cancer Center (US)
- Tel Aviv Sourasky Medical Center (IL)
Publication Details
- Journal
- British journal of surgery
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1093/bjs/znae246
- Citations
- 8
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.26
Funders
- National Cancer Institute