Knockdown of IGF2BP3 Down-Regulates PDCD4 Levels to Attenuate Hypoxic-Ischemic Brain Damage
PDCD4 and m6A reader protein IGF2BP3 were up-regulated in an HIBD neonatal rat model. Knockdown of IGF2BP3 in OGD/R-stimulated PC12 cells or PCNs alleviated cell damage through reducing PDCD4.
Authors
- Yuxia Chen (ORCID: https://orcid.org/0000-0001-5317-7887)
- Xiaoyi Fang (ORCID: https://orcid.org/0000-0002-9494-0997)
- Qianqian Fan (ORCID: https://orcid.org/0000-0002-5372-9933)
- Huayan Liu (ORCID: https://orcid.org/0000-0002-4664-0412)
Institutions
- Sun Yat-sen University (CN)
- Longgang Central Hospital (CN)
- The Seventh Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2024-09-23
- DOI
- https://doi.org/10.31083/j.fbl2909329
- Citations
- 4
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.94