Cathepsin C Promotes Tumorigenesis in Bladder Cancer by Activating the Wnt/β-catenin Signalling Pathway
CTSC was upregulated in tissues and BCa cells, and high CTSC expression was associated with poor overall survival. CTSC could enhance the activity, proliferation, migration, and invasion of BCa cells via upregulating DIAPH3 and activating the Wnt/β-catenin pathway.
Authors
- Yong Jia
- Dawen Wang (ORCID: https://orcid.org/0009-0004-2992-3797)
- Xinsheng Wang (ORCID: https://orcid.org/0000-0002-3086-5916)
Institutions
- Qingdao University (CN)
- Tianjin First Center Hospital (CN)
- Qingdao Municipal Hospital (CN)
- Second Hospital of Tianjin Medical University (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2024-09-23
- DOI
- https://doi.org/10.31083/j.fbl2909327
- Citations
- 5
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- China Postdoctoral Science Foundation