ENG is a Biomarker of Prognosis and Angiogenesis in Liver Cancer, and Promotes the Differentiation of Tumor Cells into Vascular ECs
This study found that ENG is an important biomarker of prognosis in liver cancer. Moreover, ENG is associated with endothelial cell differentiation in liver cancer and plays a crucial role in formation of the tumor vasculature. The assessment of ENG expression could be a promising strategy to identify liver cancer patients who might benefit from targeted immunotherapies.
Authors
- Jinxin Zhao (ORCID: https://orcid.org/0000-0002-0604-3541)
- Qingguo Xu (ORCID: https://orcid.org/0000-0002-2001-5133)
- Shangheng Shi (ORCID: https://orcid.org/0009-0006-2888-476X)
- Peng Jiang (ORCID: https://orcid.org/0000-0002-6057-7624)
- Yue Hu
- Cunle Zhu
Institutions
- Qingdao University (CN)
- Ningbo University (CN)
- Affiliated Hospital of Qingdao University (CN)
- Ningbo First Hospital (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2024-08-30
- DOI
- https://doi.org/10.31083/j.fbl2909315
- Citations
- 3
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.86
Funders
- National Natural Science Foundation of China