Insulin‐Like Growth Factor‐Binding Protein 5 Promotes the Cell Proliferation and Osteogenic Potential of Dental Pulp Stem Cells Dependent on Its Nuclear Localisation Sequence
Our findings suggest that cell proliferation and osteogenic differentiation effects exerted by IGFBP5 on DPSCs are closely associated with their entry into the nucleus, thereby providing a novel potential target for tissue regeneration.
Authors
- Huina Liu (ORCID: https://orcid.org/0000-0002-0722-7158)
- Ziyan Sun (ORCID: https://orcid.org/0000-0002-0713-957X)
- Jing Li (ORCID: https://orcid.org/0000-0002-5102-4315)
- Zhipeng Fan (ORCID: https://orcid.org/0000-0003-0629-3476)
Institutions
- Capital Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Shanghai Stomatological Hospital (CN)
- Stomatology Hospital (CN)
Publication Details
- Journal
- Journal of Oral Rehabilitation
- Published
- 2024-09-23
- DOI
- https://doi.org/10.1111/joor.13863
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China