The Lian-Dou-Qing-Mai Formula activates the PPARγ-LXRα-ABCA1/ABCG1 pathway by regulating IL-10, leading to the promotion of cholesterol efflux and a reduction in atherosclerotic plaques.

LDQM may affect the PPARγ/LXRα/ABCA1 signaling pathway through IL-10, regulate lipid metabolism, reduce serum inflammatory expression and lipid deposition, and improve the formation of atheroplaques.

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Publication Details

Journal
PubMed
Published
2025-04-01
DOI
https://doi.org/10.14670/hh-18-803
Citations
2
Primary Topic
Cholesterol and Lipid Metabolism
Type
article
Field-Weighted Citation Impact
4.01
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article

The Lian-Dou-Qing-Mai Formula activates the PPARγ-LXRα-ABCA1/ABCG1 pathway by regulating IL-10, leading to the promotion of cholesterol efflux and a reduction in atherosclerotic plaques.

You Li, Shu Lu, Wenqi Liao, Haoyan Zhao
2 citations
PubMed
Cholesterol and Lipid Metabolism
4.01
article

The Lian-Dou-Qing-Mai Formula activates the PPARγ-LXRα-ABCA1/ABCG1 pathway by regulating IL-10, leading to the promotion of cholesterol efflux and a reduction in atherosclerotic plaques.

You Li, Shu Lu, Wenqi Liao, Haoyan Zhao
article en
2 citations

Abstract

LDQM may affect the PPARγ/LXRα/ABCA1 signaling pathway through IL-10, regulate lipid metabolism, reduce serum inflammatory expression and lipid deposition, and improve the formation of atheroplaques.

PubMedVol. 40(4)
Nanjing University of Chinese Medicine (CN)
Openalex Percentile: Top 10%
Cholesterol and Lipid Metabolism
4.01
DOISourceOpenAlex
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The Lian-Dou-Qing-Mai Formula activates the PPARγ-LXRα-ABCA1/ABCG1 pathway by regulating IL-10, leading to the promotion of cholesterol efflux and a reduction in atherosclerotic plaques. — You Li, Shu Lu, et al. · PubMed (2025) | TGRS Research Map | TGRS