Identification and validation of ferroptosis-related biomarkers in intervertebral disc degeneration
Our study elucidates the critical role of ferroptosis in IDD and identifies specific genes, such as <i>MT1G</i> and <i>CA9</i>, as potential targets for diagnosis and therapy. These findings offer new insights into the molecular mechanisms underlying IDD and present promising avenues for future research and clinical applications.
Authors
- Zhongmin Zhang (ORCID: https://orcid.org/0000-0002-6761-6120)
- Zhongming Lai (ORCID: https://orcid.org/0000-0002-4852-8440)
- Bo Yan (ORCID: https://orcid.org/0000-0002-1267-4577)
- Cheng-shuo Fei
- Liang Wang (ORCID: https://orcid.org/0000-0002-1456-4718)
- Chenglong Li (ORCID: https://orcid.org/0000-0001-5281-3175)
- Shiyong Le
Institutions
- Third Affiliated Hospital of Southern Medical University (CN)
- Nanfang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2024-09-16
- DOI
- https://doi.org/10.3389/fcell.2024.1416345
- Citations
- 7
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 2.97
Funders
- Natural Science Foundation of Guangdong Province