A Comparison of Sanger Sequencing and Amplicon-Based Next Generation Sequencing Approaches for the Detection of HIV-1 Drug Resistance Mutations
Both the NGS systems identified additional mutations with respect to Sanger sequencing, and the agreement between them was fair. However, AD4SEQ should benefit from technical adjustments allowing higher sequence coverage.
Authors
- Maurizio Zazzi (ORCID: https://orcid.org/0000-0002-0344-6281)
- Lia Fiaschi (ORCID: https://orcid.org/0000-0003-3599-7384)
- Ilaria Vicenti (ORCID: https://orcid.org/0000-0002-4306-2960)
- Niccolò Bartolini (ORCID: https://orcid.org/0000-0002-2314-1434)
- Ilenia Varasi
- Camilla Biba
- Francesco Saladini (ORCID: https://orcid.org/0000-0002-9934-377X)
- Chiara Paletti (ORCID: https://orcid.org/0009-0004-1018-9545)
Institutions
- University of Siena (IT)
Publication Details
- Journal
- Viruses
- Published
- 2024-09-14
- DOI
- https://doi.org/10.3390/v16091465
- Citations
- 4
- Primary Topic
- HIV/AIDS drug development and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.56
Funders
- Ministero dell'Università e della Ricerca