Identification of novel biomarkers, shared molecular signatures and immune cell infiltration in heart and kidney failure by transcriptomics
This study identifies CDK2 and CCND1 as novel biomarkers linking cell cycle regulation and inflammation in heart and kidney failure. These findings offer new insights into the molecular mechanisms of HF and KF and present potential targets for diagnosis and therapy.
Authors
- Xinyu Wu (ORCID: https://orcid.org/0000-0002-1117-5098)
- Qingqing Long (ORCID: https://orcid.org/0009-0005-7265-3101)
- Ze‐Mu Wang (ORCID: https://orcid.org/0000-0003-2517-7382)
- Xinlong Zhang (ORCID: https://orcid.org/0009-0004-8040-0553)
- Fangyuan Ren
Institutions
- University of Stuttgart (DE)
- Koblenz University of Applied Sciences (DE)
- Westfälische Hochschule (DE)
- Jiangsu Province Hospital (CN)
- Nanjing Medical University (CN)
- RWTH Aachen University (DE)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-09-16
- DOI
- https://doi.org/10.3389/fimmu.2024.1456083
- Citations
- 7
- Primary Topic
- GDF15 and Related Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 3.29
Funders
- National Natural Science Foundation of China
- Government of Jiangsu Province
- Nanjing Medical University