Silibinin inhibits PM2.5-induced liver triglyceride accumulation through enhancing the function of mitochondrial Complexes I and II
Silibinin improved the accumulation of intrahepatic triglycerides induced by PM2.5, and this was, at least in part, explained by an enhancement of oxidative phosphorylation in mitochondrial Complexes I and II.
Authors
- Jingyan Han (ORCID: https://orcid.org/0000-0001-9893-2575)
- Kai Sun (ORCID: https://orcid.org/0009-0003-5746-4615)
- Yaoxuan Zhu (ORCID: https://orcid.org/0009-0007-7449-7469)
- Jingxin Zhang
- Yuxin Jin (ORCID: https://orcid.org/0009-0002-6776-1341)
- Lulu Yan (ORCID: https://orcid.org/0000-0003-0517-2269)
- Lijun Zhong
- Xinmei Huo
- Li Yin (ORCID: https://orcid.org/0009-0006-5272-7078)
- Yan Li (ORCID: https://orcid.org/0000-0003-0815-3565)
- Quan Li (ORCID: https://orcid.org/0000-0001-7512-0734)
- Dexin Li (ORCID: https://orcid.org/0000-0002-9484-0793)
- Ping Huang (ORCID: https://orcid.org/0000-0002-0221-8551)
- Xiaoqing Lu
- Chun‐Shui Pan
Institutions
- Peking University (CN)
- State Administration of Traditional Chinese Medicine of the People's Republic of China (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-09-16
- DOI
- https://doi.org/10.3389/fphar.2024.1435230
- Citations
- 1
- Primary Topic
- Silymarin and Mushroom Poisoning
- Type
- article
- Field-Weighted Citation Impact
- 0.42
Funders
- Servier