Genetic support of causal association between lipid and glucose metabolism and stress urinary incontinence in women: a bidirectional Mendelian randomization and multivariable-adjusted study
Our results reported that increased TC, LDL, and HDL are linked to higher SUI susceptibility in women, while higher FG and FI levels have a protective effect. In overweight/obese women with metabolic abnormalities, the positive associations between TC, LDL, and HDL levels and SUI indicate a higher risk.
Authors
- Nanyan Xiang
- Jin Huang (ORCID: https://orcid.org/0000-0001-8466-0089)
- Yifei Lin (ORCID: https://orcid.org/0000-0002-3184-9213)
- Tingting Fu (ORCID: https://orcid.org/0000-0003-3597-625X)
- Shiqi Su
- Yong Yang
- Yurui Luo
- Le Wang (ORCID: https://orcid.org/0009-0008-5710-2071)
Institutions
- Harvard University (US)
- Sichuan University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-09-16
- DOI
- https://doi.org/10.3389/fendo.2024.1394252
- Citations
- 6
- Primary Topic
- Pelvic floor disorders treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.82
Funders
- National Natural Science Foundation of China
- Department of Science and Technology of Sichuan Province
- Sichuan University
- National Key Research and Development Program of China
- West China Hospital, Sichuan University