Berberine alleviates ETEC-induced intestinal inflammation and oxidative stress damage by optimizing intestinal microbial composition in a weaned piglet model
Our data indicated that berberine can optimize intestinal microbiota balance and modulate the TLR4/MyD88/NF-κB and Nrf2 signaling pathways, thus helping to alleviate intestinal inflammation and oxidative damage caused by ETEC infection in weaned piglets.
Authors
- Z. Zhang
- Chunfang Zhao (ORCID: https://orcid.org/0000-0002-1744-8130)
- Xunsheng Pang
- Shenghe Li (ORCID: https://orcid.org/0000-0001-8767-6991)
- Erhui Jin (ORCID: https://orcid.org/0000-0002-5477-5317)
- Yue Wang (ORCID: https://orcid.org/0000-0002-1211-2822)
- Xiaodan Liu (ORCID: https://orcid.org/0000-0001-7474-1504)
- Xu Ji (ORCID: https://orcid.org/0000-0002-7000-7545)
- Aiyou Wen
- Feng Zhang (ORCID: https://orcid.org/0000-0002-1978-3821)
- Min Du (ORCID: https://orcid.org/0009-0007-7522-6097)
Institutions
- Anhui University of Science and Technology (CN)
- Anhui Science and Technology University (CN)
- Anhui Academy of Agricultural Sciences (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-09-16
- DOI
- https://doi.org/10.3389/fimmu.2024.1460127
- Citations
- 26
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 6.08