Pituitary Apoplexy Induced by Anticoagulant Therapy in Patient with AcuteCoronary Syndrome

Pituitary apoplexy, defined as bleeding or infarcton the pituitary gland often occurs in undiagnosed pituitary tu mors . The patientpresented to the emergency room with complaints of chest pain in the last four hours. Electrocardiographic (ECG) and laboratoryexamination results lead to an acute coronary syndrome (ACS) event. Patients were given fondaparinux, aspirin, and clopidogre l. Onthe four th day of hospitaliz ation, the patient experienced a severe headache, projectile vomiting, and double vision. Radiologicalexamination reveals a pituitary tumors apoplexy. The patient improved after a conservative approach by the surgeon. In conclusion,pituitary tumors may be a relative contraindication to dual antiplatelets and anticoagulants in acute coronary syndromes especially inpatients with renal or liver comorbidities.