A Retrospective Study on Analysis of Donor Deferral Characteristics of Plateletpheresis at a Tertiary Care Hospital in North India

Background: Platelet donation is more complicated than whole blood donation.This study scrutinizes the donor deferral parameters through retrospective analysis.Objective: The objective is to identify the factors contributing to donor deferral in the context of apheresis derived platelets.Methodology: The study spanned a year, from 1st January 2022 to 31st December 2022, and was conducted in the department of Immunohaematology and Transfusion Medicine at SMS Medical College, Jaipur, Rajasthan.It included a comprehensive screening of 972 donors.Results: Among 972 donors, 242 (24.89%) were deferred.Most deferrals were males aged 27-35 yrs.Temporary deferrals were 96%, and the rest were permanent.Common reasons were low hemoglobin (21.07%) and ABO incompatibility (16.94%).10.33% donors exhibited levels ranging from 11.5 to 12.4 gm%, reinforcing the relevance of this parameter.Conclusion: Developing countries like India face a shortage of apheresis donors.Based on our findings, we recommend revising the selection criteria of single donor plateletpheresis to suit the Indian context.