Saliva Based Diagnostics: Advancing Disease Detection through Portable Colorimetric and Electrochemical Devices

Saliva is emerging as a promising biofluid for noninvasive, realtime disease detection due to its ease of collection and rich content of diagnostic biomarkers. This paper explores the potential of saliva in identifying cancer biomarkers and other disease indicators using portable colorimetric and electrochemical devices. These technologies offer efficient, realtime detection of critical biomarkers such as proteins, metabolites, and RNA transcripts, with applications in early diagnosis of cancer and inflammatory diseases. Integrating artificial intelligence AI further enhances the precision of these devices, providing a transformative tool for personalized healthcare and continuous monitoring.