The influence of physical activity on the level of chronic inflammation in health and in non-infectious diseases

In this review we discuss the effects of exercise on systemic inflammation. The influence of moderate continuous training on humoral immunity and cellular immunity is separately considered. Recent data on the molecular mechanisms of this influence, such as myokines secreted by skeletal muscles and adipokines secreted by adipocytes, are discussed. Clinical data are provided on the effect of moderate physical activity on common diseases — cardiovascular diseases, diabetes, cancer, Alzheimer’s disease and others.