ROLE OF INDIVIDUAL MICROELEMENTS AND VITAMINS IN HASHIMOTO'S DISEASE

Introduction and objective. Hashimoto's disease is a chronic autoimmune thyroiditis. The chronic process of this disease leads to hypothyroidism. Various micronutrients and vitamins play an important role in the course of the disease and may have a significant impact on the development and treatment of Hashimoto's disease. The aim of this study is to review the literature to fully assess the impact of micronutrients on symptoms, prognosis and dynamics of change in the context of Hashimoto's disease. Articles were searched by entering keywords in PubMed databases. Scientific articles covering the period from 2016 to 2024 represent 76% of the items included in the literature. Studies from specialized research centers including meta-analyses, double-blinded randomized trials, large cross-sectional studies were considered. Studies from inexperienced centers with methodological flaws were discarded. Abbreviated description of the state of knowledge. Current treatment of clinically overt hypothyroidism is based on the use of levothyroxine. The dose of substitution treatment is determined individually for the patient depending on the symptoms observed, TSH values and age. Currently, there are no recommendations for supplementation of microelements for the disease, which is due to the need to expand research and determine which micronutrients are worth taking to increase the quality of life of patients. Conclusion. The number of cases of Hashimoto's disease is steadily increasing worldwide. Increasing attention is being paid to elements of the patient's diet and environment, in addition to the substitution treatment itself. The modification of a broadly defined lifestyle and the influence of environmental factors may in the near future find a place in the standard therapeutic management of patients with chronic autoimmune thyroiditis.