Role of Interstitial Cells of Cajal in Congenital Ureteropelvic Junction Obstruction
The significant decrease in the density of ICC at the stenotic part of UPJ compared to controls suggests a pacemaker role of these cells in ureteral peristalsis and the aetiopathogenesis of UPJ obstruction. Histopathological analysis of ICC should not only be limited to the stenotic part of UPJ but also should focus on the anastomosed ends of the ureter, which reflects post-pyeloplasty outcome.
Authors
- Lity Mohanty
- Kaumudee Pattnaik
- Pradeep Kumar Jena (ORCID: https://orcid.org/0000-0002-1291-8199)
- Sanjib Kumar Meher
- Prasanta Kumar Tripathy (ORCID: https://orcid.org/0000-0002-5070-620X)
- Pramod K. Mohanty
Institutions
- Sriram Chandra Bhanja Medical College Hospital (IN)
Publication Details
- Journal
- African Journal of Paediatric Surgery
- Published
- 2024-09-18
- DOI
- https://doi.org/10.4103/ajps.ajps_68_23
- Primary Topic
- Pediatric Urology and Nephrology Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00