Acute Liver Failure Induced by Menopausal Supplement

Drug-induced liver injury is one of the most common causes of acute liver failure in the Western world. Despite discontinuation of the offending agent, it can still tax a grim prognosis. We describe a case of a menopausal woman taking a herbal supplement to relieve hot flashes and bloating. This is the first case report of liver injury from this supplement. She initially presented with mild jaundice and elevated transaminases. Unfortunately, she rapidly progressed to encephalopathy, experienced multiorgan failure, and then died.

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Publication Details

Journal
ACG Case Reports Journal
Published
2024-09-01
DOI
https://doi.org/10.14309/crj.0000000000001509
Primary Topic
Drug-Induced Hepatotoxicity and Protection
Type
article
Field-Weighted Citation Impact
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article

Acute Liver Failure Induced by Menopausal Supplement

Zhiyong Jason Ren, Hisham ElGenaidi, Rahul P. Patel, Matthew Everwine et al.
ACG Case Reports Journal
Drug-Induced Hepatotoxicity and Protection
article

Acute Liver Failure Induced by Menopausal Supplement

Zhiyong Jason Ren, Hisham ElGenaidi, Rahul P. Patel, Matthew Everwine, HAYLE SCANLAN, Ahmed Hassan, Charles D. Snyder
article en

Abstract

Drug-induced liver injury is one of the most common causes of acute liver failure in the Western world. Despite discontinuation of the offending agent, it can still tax a grim prognosis. We describe a case of a menopausal woman taking a herbal supplement to relieve hot flashes and bloating. This is the first case report of liver injury from this supplement. She initially presented with mild jaundice and elevated transaminases. Unfortunately, she rapidly progressed to encephalopathy, experienced multiorgan failure, and then died.

ACG Case Reports JournalVol. 11(9)
Thomas Jefferson University Hospital (US), Jefferson Healthcare (US), Virtua Health (US), Louisiana State University Health Sciences Center New Orleans (US)
Good health and well-being
Openalex Percentile: Top 79%
Drug-Induced Hepatotoxicity and Protection
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Acute Liver Failure Induced by Menopausal Supplement — Zhiyong Jason Ren, Hisham ElGenaidi, et al. · ACG Case Reports Journal (2024) | TGRS Research Map | TGRS