Impact of airway closure and lung collapse on inhaled nitric oxide effect in acute lung injury: an experimental study
In an animal model of bilateral lung injury, PEEP level relative to AOP markedly influences iNO efficacy on pulmonary hemodynamics and ventilation/perfusion match, independently of oxygenation.
Authors
- Mayson Laércio de Araújo Sousa (ORCID: https://orcid.org/0000-0003-4236-5107)
- Vanessa Hsing
- Laurent Brochard (ORCID: https://orcid.org/0000-0002-7456-906X)
- Sebastián Dubó (ORCID: https://orcid.org/0000-0002-3206-0433)
- Martin Post (ORCID: https://orcid.org/0000-0003-4258-9303)
- Mariangela Pellegrini (ORCID: https://orcid.org/0000-0001-5668-7399)
- Luca S. Menga (ORCID: https://orcid.org/0000-0003-0672-3544)
Institutions
- St. Michael's Hospital (CA)
- Uppsala University Hospital (SE)
- University of Concepción (CL)
- University of Toronto (CA)
- Hospital for Sick Children (CA)
Publication Details
- Journal
- Annals of Intensive Care
- Published
- 2024-09-23
- DOI
- https://doi.org/10.1186/s13613-024-01378-z
- Citations
- 7
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 2.93
Funders
- Svenska Sällskapet för Medicinsk Forskning
- Karolinska Institutet
- Uppsala Universitet
- Canadian Institutes of Health Research