Mortality and Risk Factors of Death in Patients with AmpC β-Lactamase Producing Enterobacterales Bloodstream Infection: A Cohort Study
BSI-ESCPM is severe and has serious outcomes such as sepsis-associated deaths. Combined antibiotic therapy was a protective factor against death in patients with BSI-ESCPM. There is a suggestive association between inadequate antibiotic therapy and mortality. The ESCPM group bacteria that are considered to be at moderate to high risk of clinically significant AmpC production were not associated with death.
Authors
- Fernanda Moreth do Valle
- Ianick Souto Martins (ORCID: https://orcid.org/0000-0002-3260-2554)
- Jaqueline Rocha (ORCID: https://orcid.org/0000-0003-1651-9483)
- Natália Chilinque Zambão da Silva
- Ana Sheila Duarte Nunes Silva (ORCID: https://orcid.org/0000-0001-7606-608X)
- Shelley Ehrlich (ORCID: https://orcid.org/0000-0003-3861-1950)
Institutions
- Cincinnati Children's Hospital Medical Center (US)
- Universidade Federal Fluminense (BR)
- Hospital do Câncer III (BR)
- Hospital Universitário Antônio Pedro (BR)
- Instituto Nacional de Câncer - INCA (BR)
- University of Cincinnati (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2024-09-01
- DOI
- https://doi.org/10.2147/idr.s473789
- Citations
- 4
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.68
Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro