Antimicrobial activities of Diltiazem Hydrochloride: drug repurposing approach
This study suggests that Diltiazem HCl, in addition to its antihypertensive effect, may also be a potential treatment option for infections caused by Gram-positive bacteria and the CoxB4 viruses, providing an additional off-target effect for Diltiazem HCl.
Authors
- O. Al-Duaij (ORCID: https://orcid.org/0000-0001-6290-2892)
- Sharif Abu Alrub
- Sabry A. H. Zidan (ORCID: https://orcid.org/0000-0003-4975-5933)
- Rageh K. Hussein
Institutions
- Al-Azhar University (EG)
- Imam Mohammad ibn Saud Islamic University (SA)
- Assiut University (EG)
Publication Details
- Journal
- PeerJ
- Published
- 2024-09-23
- DOI
- https://doi.org/10.7717/peerj.17809
- Citations
- 3
- Primary Topic
- Phenothiazines and Benzothiazines Synthesis and Activities
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- Al-Imam Muhammad Ibn Saud Islamic University
- Al-Azhar University