Exacerbation of Fragile X-associated Tremor/Ataxia Syndrome in the Context of COVID-19 Infection: A Case Report

Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurodegenerative disorder affecting premutation carriers of the FMR1 gene. This case report presents a 65-year-old male who was diagnosed with FXTAS after presenting with an acute exacerbation of neurological symptoms in the setting of a COVID-19 infection. The case highlights the potential for viral infections to trigger the worsening of FXTAS symptoms and emphasizes the importance of comprehensive evaluation in such scenarios.

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Publication Details

Journal
Cureus
Published
2024-09-23
DOI
https://doi.org/10.7759/cureus.69969
Primary Topic
Genetics and Neurodevelopmental Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Exacerbation of Fragile X-associated Tremor/Ataxia Syndrome in the Context of COVID-19 Infection: A Case Report

Rebecca Patel, Hussein Ghasham, Heather Heild
Cureus
Genetics and Neurodevelopmental Disorders
article

Exacerbation of Fragile X-associated Tremor/Ataxia Syndrome in the Context of COVID-19 Infection: A Case Report

Rebecca Patel, Hussein Ghasham, Heather Heild
article en

Abstract

Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurodegenerative disorder affecting premutation carriers of the FMR1 gene. This case report presents a 65-year-old male who was diagnosed with FXTAS after presenting with an acute exacerbation of neurological symptoms in the setting of a COVID-19 infection. The case highlights the potential for viral infections to trigger the worsening of FXTAS symptoms and emphasizes the importance of comprehensive evaluation in such scenarios.

CureusVol. 16(9)
HealthCare Partners Medical Group (US), Touro University Nevada (US)
Good health and well-being
Openalex Percentile: Top 82%
Genetics and Neurodevelopmental Disorders
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