Isolation, Identification and Biological Evaluation of aNovel Protein from Spergulaarvensis

Researchers are looking into peptides as an alternative anticancer agent to address the limitations of present medicines.Spergula arvensis, an edible plant, has been employed against pulmonary tuberculosis.No anticancer activity, however, has been reported for this plant and hence the present study.The plant Spergula arvensis was subjected to detailed analysis and proteins were isolated, purified and evaluated for their anticancer activity.In vitro anticancer activity was carried out using "HeLa (Cervical Cancer)", A549 (Lung carcinoma), Hep2 (Larynx carcinoma) and "OAW42 (Ovary cancer Cells)" cell lines.Results reveal that the bioactive protein isolated has a molecular weight of approximately 52kDa and shows potent activity against the cervical cell line, HeLa.The anticancer efficacy of a plant protein isolated from Spergula arvensis is impressive.

Authors

Publication Details

Journal
African Journal of Biomedical Research
Published
2024-09-23
DOI
https://doi.org/10.53555/ajbr.v27i1s.1833
Primary Topic
Medicinal Plants and Bioactive Compounds
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Isolation, Identification and Biological Evaluation of aNovel Protein from Spergulaarvensis

Mahalakshmi Sundarapandian
African Journal of Biomedical Research
Medicinal Plants and Bioactive Compounds
article

Isolation, Identification and Biological Evaluation of aNovel Protein from Spergulaarvensis

Mahalakshmi Sundarapandian
article en

Abstract

Researchers are looking into peptides as an alternative anticancer agent to address the limitations of present medicines.Spergula arvensis, an edible plant, has been employed against pulmonary tuberculosis.No anticancer activity, however, has been reported for this plant and hence the present study.The plant Spergula arvensis was subjected to detailed analysis and proteins were isolated, purified and evaluated for their anticancer activity.In vitro anticancer activity was carried out using "HeLa (Cervical Cancer)", A549 (Lung carcinoma), Hep2 (Larynx carcinoma) and "OAW42 (Ovary cancer Cells)" cell lines.Results reveal that the bioactive protein isolated has a molecular weight of approximately 52kDa and shows potent activity against the cervical cell line, HeLa.The anticancer efficacy of a plant protein isolated from Spergula arvensis is impressive.

African Journal of Biomedical Research
Zero hunger
Openalex Percentile: Top 86%
Medicinal Plants and Bioactive Compounds
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.