DNA methylation-mediated FGFR1 silencing enhances NF-κB signaling: implications for asthma pathogenesis
Our findings reveal a potential mechanism involving <i>FGFR1</i> in the progression of asthma. DNA methylation of <i>FGFR1</i> inactivates the NF-ĸB signaling pathway, suggesting a promising avenue for developing effective therapeutic strategies for asthma.
Authors
- Roshan Kumar Mahato (ORCID: https://orcid.org/0009-0009-9434-1650)
- Jianguo Xu (ORCID: https://orcid.org/0000-0001-9903-9471)
- Chen Gao (ORCID: https://orcid.org/0000-0001-9372-8014)
- Minglu Meng
- Yingjiao Ma
Institutions
- Khon Kaen University (TH)
- Affiliated Hospital of Youjiang Medical University for Nationalities (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2024-09-23
- DOI
- https://doi.org/10.3389/fmolb.2024.1433557
- Citations
- 1
- Primary Topic
- Fibroblast Growth Factor Research
- Type
- article
- Field-Weighted Citation Impact
- 0.23