LRRK2<sup>G2019S</sup> Gene Mutation Causes Skeletal Muscle Impairment in Animal Model of Parkinson's Disease

Taken together, these findings may provide new insights into the clinical and pathogenic involvement of LRRK2<sup>G2019</sup> mutation in muscles, suggesting that the diseases may affect not only midbrain dopaminergic neurons, but also other tissues, and it may help overall clinical management of this devastating disease.

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Publication Details

Journal
Journal of Cachexia Sarcopenia and Muscle
Published
2024-09-23
DOI
https://doi.org/10.1002/jcsm.13604
Citations
4
Primary Topic
Muscle Physiology and Disorders
Type
article
Field-Weighted Citation Impact
0.94

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article

LRRK2G2019S Gene Mutation Causes Skeletal Muscle Impairment in Animal Model of Parkinson's Disease

Weidong Le, Chunli Song, Tianbai Li, Murad Al‐Nusaif et al.
4 citations
Journal of Cachexia Sarcopenia and Muscle
Muscle Physiology and Disorders
0.94
article

LRRK2G2019S Gene Mutation Causes Skeletal Muscle Impairment in Animal Model of Parkinson's Disease

Weidong Le, Chunli Song, Tianbai Li, Murad Al‐Nusaif, Lulu Tian, Yiying Hu, Cheng Cheng, Panpan Wang, Song Li, Zhanhua Liang, Huijia Yang
article en
4 citations

Abstract

Taken together, these findings may provide new insights into the clinical and pathogenic involvement of LRRK2<sup>G2019</sup> mutation in muscles, suggesting that the diseases may affect not only midbrain dopaminergic neurons, but also other tissues, and it may help overall clinical management of this devastating disease.

Journal of Cachexia Sarcopenia and MuscleVol. 15(6)
Dalian Medical University (CN), First Affiliated Hospital of Dalian Medical University (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 25%
Muscle Physiology and Disorders
0.94
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LRRK2<sup>G2019S</sup> Gene Mutation Causes Skeletal Muscle Impairment in Animal Model of Parkinson's Disease — Weidong Le, Chunli Song, et al. · Journal of Cachexia Sarcopenia and Muscle (2024) | TGRS Research Map | TGRS