Prevalence of adrenal rest tumors and course of gonadal dysfunction in a clinical sample of men with congenital adrenal hyperplasia: a longitudinal analysis over 10 years

T levels below the normal range are frequent in men with 21OHD, regardless of TART, but change little over time. Besides adrenal androgen control gonadal axis suppression from supraphysiological glucocorticoid dosages needs to be considered. While our results do not endorse regular screening for alterations in TART status among adults, Sertoli cell function should be monitored in men with large TART.

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Publication Details

Journal
European Journal of Endocrinology
Published
2024-08-30
DOI
https://doi.org/10.1093/ejendo/lvae112
Citations
1
Primary Topic
Sexual Differentiation and Disorders
Type
article
Field-Weighted Citation Impact
0.23

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article

Prevalence of adrenal rest tumors and course of gonadal dysfunction in a clinical sample of men with congenital adrenal hyperplasia: a longitudinal analysis over 10 years

H. Nowotny, Christian Lottspeich, Eva Rieger, Nicole Reisch et al.
1 citations
European Journal of Endocrinology
Sexual Differentiation and Disorders
0.23
article

Prevalence of adrenal rest tumors and course of gonadal dysfunction in a clinical sample of men with congenital adrenal hyperplasia: a longitudinal analysis over 10 years

H. Nowotny, Christian Lottspeich, Eva Rieger, Nicole Reisch, Richard Joseph Auchus, Martin Bidlingmaier, Lea Tschaidse, Matthias K. Auer, Duygu Büyükerzurmulu
article en
1 citations

Abstract

T levels below the normal range are frequent in men with 21OHD, regardless of TART, but change little over time. Besides adrenal androgen control gonadal axis suppression from supraphysiological glucocorticoid dosages needs to be considered. While our results do not endorse regular screening for alterations in TART status among adults, Sertoli cell function should be monitored in men with large TART.

European Journal of EndocrinologyVol. 191(3)
University of Michigan (US), LMU Klinikum (DE), Ludwig-Maximilians-Universität München (DE)
Deutsche Forschungsgemeinschaft
Good health and well-being
Openalex Percentile: Top 42%
Sexual Differentiation and Disorders
0.23
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Prevalence of adrenal rest tumors and course of gonadal dysfunction in a clinical sample of men with congenital adrenal hyperplasia: a longitudinal analysis over 10 years — H. Nowotny, Christian Lottspeich, et al. · European Journal of Endocrinology (2024) | TGRS Research Map | TGRS