Prospective Evaluation of Transsphenoidal Pituitary Surgery in Patients with Cushing’s Disease: Delayed Remission and the Role of Postsurgical Cortisol as a Predictive Factor
In our cohort of patients, the endoscopic transsphenoidal approach was safe and effective in the treatment of Cushing's disease. We demonstrated that serum and urinary cortisol concentrations did not experience significant fluctuations from the first to the fifth day. This constitutes an accurate predictor of durable remission, comprising a distinctive finding in the intermediate term by our team.
Authors
- Enrico Alexandre (ORCID: https://orcid.org/0000-0002-5227-341X)
- Luca Denaro (ORCID: https://orcid.org/0000-0002-2529-6149)
- Enzo Emanuelli (ORCID: https://orcid.org/0000-0002-2422-5402)
- Maria Baldovin (ORCID: https://orcid.org/0000-0002-1557-9321)
- Jiannis Hajiioannou (ORCID: https://orcid.org/0000-0003-2312-7218)
- Diego Cazzador (ORCID: https://orcid.org/0000-0001-7272-7469)
- Claudia Zanotti
- Sara Munari
- Athanasios Saratziotis (ORCID: https://orcid.org/0000-0002-2393-4012)
Institutions
- University of Pisa (IT)
- University of Padua (IT)
- University Hospital of Larissa (GR)
- Ca' Foncello Hospital (IT)
- Azienda Ospedaliera Universitaria Pisana (IT)
Publication Details
- Journal
- Healthcare
- Published
- 2024-09-22
- DOI
- https://doi.org/10.3390/healthcare12181900
- Citations
- 1
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.36