Role of Mesenchymal Stem Cells in Growth of Bone Grafting, Distraction of Bones and in Kummoona Chondro-Osseous Graft

Mesenchymal stem cells play important role in reconstruction of temporomandibular joint (TMJ) by Kummoona chondro-osseous graft from iliac crest for restoration of normal biological function in growth, remodeling and repair.Stem cells also play a role in growth of bone graft of lower jaw.These cells also participate in growth of distraction of jaws and short limb in children.These studies were supported by experimental studies on Rabbits to prove the ability of mesenchymal stem cells in growth of bones.Histological studies showed enormous changes by formation of clot due to platelets aggregation, with releasing growth factor (PGF) and formation of healthy granulation tissues Mesenchymal stem cells were originated from bone marrow, released to periosteum and covering muscles.