Coexistence of HHV-8-associated plasmacytic multicentric Castleman disease, Kaposi’s sarcoma, and multiple myeloma in a HIV-negative patient

Multicentric Castleman disease (MCD), often linked with human herpesvirus-8 (HHV-8) and Kaposi's sarcoma, is rare and aggressive condition, particularly in human immunodeficiency virus (HIV)-positive patients.The coexistence of MCD, Kaposi's sarcoma, and multiple myeloma is exceptionally rare in HIV-negative, immunocompetent patient.This case highlights the challenges in diagnosing and managing complex presentations of MCD and related malignancies, with poor outcomes despite treatment.

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Publication Details

Journal
European Journal of Case Reports in Internal Medicine
Published
2024-09-23
DOI
https://doi.org/10.12890/2024_004876
Citations
2
Primary Topic
Viral-associated cancers and disorders
Type
article
Field-Weighted Citation Impact
0.57
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article

Coexistence of HHV-8-associated plasmacytic multicentric Castleman disease, Kaposi’s sarcoma, and multiple myeloma in a HIV-negative patient

Ümi̇t Yavuz Malkan, Murat Özdede, Olgu Erkin Çınar, Rashad İsmayılov et al.
2 citations
European Journal of Case Reports in Internal Medicine
Viral-associated cancers and disorders
0.57
article

Coexistence of HHV-8-associated plasmacytic multicentric Castleman disease, Kaposi’s sarcoma, and multiple myeloma in a HIV-negative patient

Ümi̇t Yavuz Malkan, Murat Özdede, Olgu Erkin Çınar, Rashad İsmayılov, Ece Özoğul, İbrahim Güllü, Ayşegül Üner
article en
2 citations

Abstract

Multicentric Castleman disease (MCD), often linked with human herpesvirus-8 (HHV-8) and Kaposi's sarcoma, is rare and aggressive condition, particularly in human immunodeficiency virus (HIV)-positive patients.The coexistence of MCD, Kaposi's sarcoma, and multiple myeloma is exceptionally rare in HIV-negative, immunocompetent patient.This case highlights the challenges in diagnosing and managing complex presentations of MCD and related malignancies, with poor outcomes despite treatment.

European Journal of Case Reports in Internal MedicineVol. 11(10)
Hacettepe University Hospital (TR), Hacettepe University (TR)
Good health and well-being
Openalex Percentile: Top 28%
Viral-associated cancers and disorders
0.57
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Coexistence of HHV-8-associated plasmacytic multicentric Castleman disease, Kaposi’s sarcoma, and multiple myeloma in a HIV-negative patient — Ümi̇t Yavuz Malkan, Murat Özdede, et al. · European Journal of Case Reports in Internal Medicine (2024) | TGRS Research Map | TGRS