pH-Responsive Block Copolymer Micelles of Temsirolimus: Preparation, Characterization and Antitumor Activity Evaluation
In conclusion, we successfully prepared pH-responsive TEM-loaded micelles. The results showed that pH-responsive TEM-loaded micelles can achieve passive tumor targeting of TEM, and take advantage of the acidic conditions in tumor tissues to achieve rapid drug release.
Authors
- Xiaolan Lin
- Fangqing Cai
- Weijie Liang (ORCID: https://orcid.org/0000-0002-0833-350X)
- Yuting Wang (ORCID: https://orcid.org/0000-0003-2347-2417)
- Yixuan Li (ORCID: https://orcid.org/0000-0002-3550-8192)
- Junshan Ruan (ORCID: https://orcid.org/0000-0002-6462-2357)
- Cunze Wang (ORCID: https://orcid.org/0000-0002-7751-1242)
- Caiyu Liu
- Ling Wang (ORCID: https://orcid.org/0000-0002-5176-7469)
Institutions
- Fujian Medical University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2024-09-01
- DOI
- https://doi.org/10.2147/ijn.s469913
- Citations
- 3
- Primary Topic
- Nanoparticle-Based Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.52