Synthesis of Metal–Organic Cages via Orthogonal Bond Cleavage in 3D Metal–Organic Frameworks
Herein we address the question of whether a supramolecular finite metal-organic structure such as a cage or metal-organic polyhedron (MOP) can be synthesized via controlled cleavage of a three-dimensional (3D) metal-organic structure. To demonstrate this, we report the synthesis of a Cu(II)-based cuboctahedral MOP through orthogonal olefinic bond cleavage of the cavities of a 3D, Cu(II)-based, metal-organic framework (MOF). Additionally, we demonstrate that controlling the ozonolysis conditions used for the cleavage enables Clip-off Chemistry synthesis of two cuboctahedral MOPs that differ by their external functionalization: one in which all 24 external groups represent a mixture of aldehydes, carboxylic acids, acetals and esters, and one in which all are aldehydes.
Authors
- Inhar Imaz (ORCID: https://orcid.org/0000-0002-0278-1141)
- Judith Juanhuix (ORCID: https://orcid.org/0000-0003-3728-8215)
- Jorge Albalad (ORCID: https://orcid.org/0000-0001-5850-6723)
- Dongsik Nam (ORCID: https://orcid.org/0000-0002-9941-3504)
- Daniel Maspoch (ORCID: https://orcid.org/0000-0003-1325-9161)
- Sara Ruiz‐Relaño
- Alba Cortés‐Martínez
Institutions
- Institució Catalana de Recerca i Estudis Avançats (ES)
- Universitat Autònoma de Barcelona (ES)
- ALBA Synchrotron (Spain) (ES)
- Institut Català de Nanociència i Nanotecnologia (ES)
Publication Details
- Journal
- Journal of the American Chemical Society
- Published
- 2024-09-23
- DOI
- https://doi.org/10.1021/jacs.4c09431
- Citations
- 17
- Primary Topic
- Metal-Organic Frameworks: Synthesis and Applications
- Type
- article
- Field-Weighted Citation Impact
- 2.69
Funders
- Centres de Recerca de Catalunya
- Institut Català de Nanociència i Nanotecnologia
- European Commission
- Generalitat de Catalunya
- Institució Catalana de Recerca i Estudis Avançats
- Ministerio de Ciencia e Innovación
- Agència de Gestió d'Ajuts Universitaris i de Recerca
- European Regional Development Fund
- Agencia Estatal de Investigación
- H2020 European Research Council