Directed protein engineering identifies a human TIM-4 blocking antibody that enhances anti-tumor response to checkpoint inhibition in murine colon carcinoma
Our study has demonstrated a rapid antibody discovery approach and identified a novel human TIM-4 antibody that can serve as a therapeutic for antitumor immunity to improve cancer therapy.
Authors
- Laura Padula
- Kamala Anumukonda
- Neil I. Goldstein
- Karla K. Frietze (ORCID: https://orcid.org/0000-0002-4708-8009)
- Natasha Strbo
Institutions
- University of Miami (US)
Publication Details
- Journal
- Antibody Therapeutics
- Published
- 2024-09-23
- DOI
- https://doi.org/10.1093/abt/tbae026
- Citations
- 1
- Primary Topic
- Galectins and Cancer Biology
- Type
- article
- Field-Weighted Citation Impact
- 0.24
Funders
- University of Miami