Differences in brain structure and cognitive performance between patients with long-COVID and those with normal recovery
Differences in diffusivity between long-COVID and normal recovery groups were found on only one DTI metric. This could represent subtle areas of pathology such as gliosis or edema, but the small effect sizes and non-specific nature of the diffusion indices make pathological inference difficult. Although long-COVID patients reported many neuropsychiatric symptoms, significant differences in objective cognitive performance were not found.
Authors
- Breanna Nelson
- William G. Honer (ORCID: https://orcid.org/0000-0002-7628-5108)
- Donna J. Lang (ORCID: https://orcid.org/0000-0001-9373-1555)
- Johnson Chen (ORCID: https://orcid.org/0000-0001-7794-9992)
- Wayne Su (ORCID: https://orcid.org/0000-0001-9127-9008)
- Cheryl L. Wellington (ORCID: https://orcid.org/0000-0001-7014-039X)
- William J. Panenka (ORCID: https://orcid.org/0000-0001-7143-6512)
- A. Jon Stoessl (ORCID: https://orcid.org/0000-0002-9778-7246)
- Vesna Sossi (ORCID: https://orcid.org/0000-0001-7862-5711)
- Mypinder S. Sekhon (ORCID: https://orcid.org/0000-0002-4487-301X)
- Noah D. Silverberg (ORCID: https://orcid.org/0000-0001-6378-148X)
- Ava Grier
- Lea N Farah
Institutions
- University of British Columbia Hospital (CA)
- University of British Columbia (CA)
- Vancouver General Hospital (CA)
- BC Mental Health & Substance Use Services (CA)
- BC Children's Hospital (CA)
Publication Details
- Journal
- NeuroImage
- Published
- 2024-09-23
- DOI
- https://doi.org/10.1016/j.neuroimage.2024.120859
- Citations
- 9
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 3.32
Funders
- Weston Brain Institute