Dihydrotestosterone Enhances MICA-Mediated Immune Responses to Epstein–Barr Virus-Associated Gastric Carcinoma
DHT enhances the immune response against EBVaGC by upregulating MICA and activating NK and T cells. These findings suggest potential therapeutic strategies targeting androgen signaling to improve anti-tumor immunity in EBVaGC.
Authors
- Inuk Jung (ORCID: https://orcid.org/0000-0003-0675-4244)
- Hyosun Cho (ORCID: https://orcid.org/0000-0001-9131-5742)
- Miyeon Cho (ORCID: https://orcid.org/0000-0002-8326-8963)
- Sohyun Youn
- Hyojeung Kang (ORCID: https://orcid.org/0000-0002-0622-5839)
- Jun Ho Lee (ORCID: https://orcid.org/0000-0002-4075-3504)
- Sun Hee Lee (ORCID: https://orcid.org/0000-0002-0332-6917)
- Dong‐Hyun Seo
- Hyeji Byun
Institutions
- Kyungpook National University (KR)
- Duksung Women's University (KR)
Publication Details
- Journal
- Cancers
- Published
- 2024-09-21
- DOI
- https://doi.org/10.3390/cancers16183219
- Citations
- 4
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.96
Funders
- National Research Foundation of Korea