Effect of magnetic anisotropy and interaction on spatial focused hyperthermia for rotating and oscillating fields

The behavior of magnetic nanoparticles in a time-varying magnetic field has several practical applications. One of these is hyperthermia used in the treatment of cancer. The nanoparticles injected in the tumor cells release the energy absorbed from the time dependent external magnetic field in the form of heat to its environment in a well-localized way. The aim of the research in this area is to maximize the amount of the dissipated energy. Using a combination of an oscillating and static magnetic field, this dissipated energy can be more focused in space. In this article, we investigated whether this spatial focusing is also present using a rotating and static field together. Furthermore, we investigated the effects of anisotropy and interaction between nanoparticles on this spatial focusing effect using the jump-diffusion model for Néel relaxation in both cases. This kinetic Monte Carlo (MC) method was validated and compared with the stochastic Landau-Lifshitz-Gilbert (SLLG) equation based model. We have shown that the spatial focusing effect is also present for these non-idealized experimentally realizable cases. Also, the effect of rotating magnetic field on magnetic nanoparticles was not investigated in kinetic Monte Carlo simulations before.