Infections following chimeric antigen receptor T cell therapy: 2018–2022
COVID-19 and C. difficile infection were the most common infections following CAR T-cell therapy. Most infections occurred within the first 100 days. Empiric antibiotic use and C. difficile infection were common in patients with CRS/ICANS, in the absence of documented bacterial infection, thus providing an excellent opportunity for antimicrobial stewardship in this population.
Authors
- Pranatharthi Chandrasekar (ORCID: https://orcid.org/0000-0003-0774-1058)
- Lea Monday (ORCID: https://orcid.org/0000-0002-4446-2632)
- Vishakh C Keri (ORCID: https://orcid.org/0000-0003-1109-8739)
- Mahmoud Al‐Saadi
- Abhinav Deol (ORCID: https://orcid.org/0000-0003-0947-8871)
- Rahul Vyas (ORCID: https://orcid.org/0000-0002-7980-4321)
- Jahanavi M. Ramakrishna (ORCID: https://orcid.org/0000-0002-9650-8292)
Institutions
- Wayne State University (US)
- The Barbara Ann Karmanos Cancer Institute (US)
Publication Details
- Journal
- Transplant Infectious Disease
- Published
- 2024-09-23
- DOI
- https://doi.org/10.1111/tid.14376
- Citations
- 3
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.85