Human Ascaris infection is associated with higher frequencies of IL-10 producing B cells
A. lumbricoides infection has a significant impact on the immune response, particularly on Breg cell populations and antibody responses. Our findings suggest that A. lumbricoides infection mediates a dose-dependent immunosuppressive response characterized by an increase in Breg cells and concomitant suppression of ABA-1-specific humoral responses.
Authors
- Luis Caraballo (ORCID: https://orcid.org/0000-0002-5204-1109)
- Josefina Zakzuk (ORCID: https://orcid.org/0000-0002-6007-5376)
- Cezmi A. Akdiş (ORCID: https://orcid.org/0000-0001-8020-019X)
- Willem van de Veen (ORCID: https://orcid.org/0000-0001-9951-6688)
- Juan Felipe Valdés‐López (ORCID: https://orcid.org/0000-0003-3691-4501)
- Mübeccel Akdis M
Institutions
- University of Cartagena (CO)
- University of Zurich (CH)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2024-09-23
- DOI
- https://doi.org/10.1371/journal.pntd.0012520
- Citations
- 5
- Primary Topic
- Parasites and Host Interactions
- Type
- article
- Field-Weighted Citation Impact
- 2.58
Funders
- Christine Kühne – Center for Allergy Research and Education