People Living With HIV Have More Intact HIV DNA in Circulating CD4+ T Cells if They Have History of Pulmonary Tuberculosis

People living with HIV with a history of active pulmonary TB have more HIV pro-virus in their circulating CD4+ T cells, even years after TB cure. We need to characterize which CD4+ T cells are harboring intact provirus to consider the impact of T cell-targeting HIV cure interventions for people living in TB-endemic areas.

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Publication Details

Journal
Pathogens and Immunity
Published
2024-09-23
DOI
https://doi.org/10.20411/pai.v9i2.722
Citations
2
Primary Topic
HIV Research and Treatment
Type
article
Field-Weighted Citation Impact
0.59

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article

People Living With HIV Have More Intact HIV DNA in Circulating CD4+ T Cells if They Have History of Pulmonary Tuberculosis

Ali Danesh, Jean W. Pape, Alexandra Apollon, Winiffer Conce Alberto et al.
2 citations
Pathogens and Immunity
HIV Research and Treatment
0.59
article

People Living With HIV Have More Intact HIV DNA in Circulating CD4+ T Cells if They Have History of Pulmonary Tuberculosis

Ali Danesh, Jean W. Pape, Alexandra Apollon, Winiffer Conce Alberto, Yvetot Joseph, Uchenna Chukwukere, Daniel W. Fitzgerald, Yanique Duffus, Myung Hee Lee, R. Brad Jones, Kathryn Dupnik, Marc Antoine Jean Juste, Dominique Lespinasse, Maureen M. Ward, Parmida Jamshidi, Esther Brill
article en
2 citations

Abstract

People living with HIV with a history of active pulmonary TB have more HIV pro-virus in their circulating CD4+ T cells, even years after TB cure. We need to characterize which CD4+ T cells are harboring intact provirus to consider the impact of T cell-targeting HIV cure interventions for people living in TB-endemic areas.

Pathogens and ImmunityVol. 9(2)
Cornell University (US), Gheskio Centers (HT), Weill Cornell Medicine (US)
National Institutes of Health, National Center for Advancing Translational Sciences
Good health and well-being
Openalex Percentile: Top 32%
HIV Research and Treatment
0.59
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People Living With HIV Have More Intact HIV DNA in Circulating CD4+ T Cells if They Have History of Pulmonary Tuberculosis — Ali Danesh, Jean W. Pape, et al. · Pathogens and Immunity (2024) | TGRS Research Map | TGRS