Gabapentin Dosing Guidance: a Multimodal Approach to Topical and Oral Concomitant Therapy

As researchers in pain management search for safer alternatives to oral analgesics, transdermal or externally applied analgesic options are becoming increasingly available. The search for therapeutic alternatives is fueled by not only the risk of misuse of opioids and similar CNS depressant drugs, but also the impact that chronic pain has on a patient’s quality of life. In this review, we determine an approach by which topical and oral gabapentin can be used safely and effectively, either as monotherapy, or as synergistic concomitant therapy.